BDBM22316 4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}sulfamoyl)-N-(2-hydroxyethyl)-N-methylbenzamide::tryptamine sulfonamide, 40i

SMILES: CN(CCO)C(=O)c1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1

InChI Key: InChIKey=PIQRJIRBRUZQQL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22316 (4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}s...) Show SMILES CN(CCO)C(=O)c1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1 Show InChI InChI=1S/C28H27N3O5S/c1-31(16-17-32)28(33)19-10-12-21(13-11-19)37(34,35)29-15-14-23-22-7-3-4-8-24(22)30-27(23)26-18-20-6-2-5-9-25(20)36-26/h2-13,18,29-30,32H,14-17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
					More data for this Ligand-Target Pair