BDBM22317 4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}sulfamoyl)-N-[2-(dimethylamino)ethyl]-N-methylbenzamide::tryptamine sulfonamide, 40j

SMILES: CN(C)CCN(C)C(=O)c1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1

InChI Key: InChIKey=NCQIGJNVOCUQKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22317 (4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}s...) Show SMILES CN(C)CCN(C)C(=O)c1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1 Show InChI InChI=1S/C30H32N4O4S/c1-33(2)18-19-34(3)30(35)21-12-14-23(15-13-21)39(36,37)31-17-16-25-24-9-5-6-10-26(24)32-29(25)28-20-22-8-4-7-11-27(22)38-28/h4-15,20,31-32H,16-19H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
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