BDBM224608 US10202383, Example 2(256)::US9321791, 2(256)::US9556175, 2(256)

SMILES: CC#CCn1c(nc2n(C)c(=O)n(C\C=C\c3c(F)c(F)c(F)c(F)c3F)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key: InChIKey=NOYHGXVDSPKVCK-STMXVASLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224608 (US10202383, Example 2(256) | US9321791, 2(256) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(C\C=C\c3c(F)c(F)c(F)c(F)c3F)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C24H23F5N6O2/c1-3-4-10-34-20-21(31-23(34)33-9-5-7-13(30)12-33)32(2)24(37)35(22(20)36)11-6-8-14-15(25)17(27)19(29)18(28)16(14)26/h6,8,13H,5,7,9-12,30H2,1-2H3/b8-6+/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224608 (US10202383, Example 2(256) | US9321791, 2(256) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(C\C=C\c3c(F)c(F)c(F)c(F)c3F)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C24H23F5N6O2/c1-3-4-10-34-20-21(31-23(34)33-9-5-7-13(30)12-33)32(2)24(37)35(22(20)36)11-6-8-14-15(25)17(27)19(29)18(28)16(14)26/h6,8,13H,5,7,9-12,30H2,1-2H3/b8-6+/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224608 (US10202383, Example 2(256) | US9321791, 2(256) | U...) Show SMILES CC#CCn1c(nc2n(C)c(=O)n(C\C=C\c3c(F)c(F)c(F)c(F)c3F)c(=O)c12)N1CCC[C@@H](N)C1 Show InChI InChI=1S/C24H23F5N6O2/c1-3-4-10-34-20-21(31-23(34)33-9-5-7-13(30)12-33)32(2)24(37)35(22(20)36)11-6-8-14-15(25)17(27)19(29)18(28)16(14)26/h6,8,13H,5,7,9-12,30H2,1-2H3/b8-6+/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair