null
SMILES: CNc1nnc(s1)-c1ccc2[nH]cc(-c3ccc(s3)-c3cccs3)c2c1
InChI Key: InChIKey=FGWZFENEZPJNPG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM224974 (US9321756, 241) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 414 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)... | US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM224974 (US9321756, 241) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)... | US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM224974 (US9321756, 241) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AMGEN INC. US Patent | Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)... | US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2 | |||||||||||
More data for this Ligand-Target Pair |