BDBM22608 N-[(4-fluorophenyl)methyl]-5,6-dihydroxy-2-(1-methylpyrrolidin-2-yl)pyrimidine-4-carboxamide::dihydroxypyrimidine deriv., 8

SMILES: CN1CCCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)[nH]1

InChI Key: InChIKey=BUYKZKKPQMDSSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22608 (N-[(4-fluorophenyl)methyl]-5,6-dihydroxy-2-(1-meth...) Show SMILES CN1CCCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)[nH]1 Show InChI InChI=1S/C17H19FN4O3/c1-22-8-2-3-12(22)15-20-13(14(23)17(25)21-15)16(24)19-9-10-4-6-11(18)7-5-10/h4-7,12,23H,2-3,8-9H2,1H3,(H,19,24)(H,20,21,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.8	37
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 50: 4953-75 (2007) Article DOI: 10.1021/jm0704705 BindingDB Entry DOI: 10.7270/Q2BZ64BS
					More data for this Ligand-Target Pair