BDBM226280 US9321790, 92
SMILES: FC(F)(F)C1CCn2c(nc(cc2=O)N2C[C@@H]3C[C@H]2CO3)N1CCC1CCOCC1
InChI Key: InChIKey=VKLNFKDGJLODJH-KSCSMHSMSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM226280![]() (US9321790, 92) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Sanofi US Patent | Assay Description The compounds according to the invention underwent pharmacological trials to measure the selectivity toward human lipid kinases and especially human ... | US Patent US9321790 (2016) BindingDB Entry DOI: 10.7270/Q2KD1WSG | |||||||||||
More data for this Ligand-Target Pair |