BDBM22657 N-Me-pyrimidone deriv., 56::N-[(3-bromophenyl)methyl]-5-hydroxy-1-methyl-2-(4-methylmorpholin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

SMILES: CN1CCOCC1c1nc(C(=O)NCc2cccc(Br)c2)c(O)c(=O)n1C

InChI Key: InChIKey=PEBWIPMJIWZNLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22657 (N-Me-pyrimidone deriv., 56 | N-[(3-bromophenyl)met...) Show SMILES CN1CCOCC1c1nc(C(=O)NCc2cccc(Br)c2)c(O)c(=O)n1C Show InChI InChI=1S/C18H21BrN4O4/c1-22-6-7-27-10-13(22)16-21-14(15(24)18(26)23(16)2)17(25)20-9-11-4-3-5-12(19)8-11/h3-5,8,13,24H,6-7,9-10H2,1-2H3,(H,20,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 50: 4953-75 (2007) Article DOI: 10.1021/jm0704705 BindingDB Entry DOI: 10.7270/Q2BZ64BS
					More data for this Ligand-Target Pair