BDBM22672 Bicyclic pyrimidinone, 10c::N-[(4-fluorophenyl)methyl]-3-hydroxy-10-(morpholin-4-yl)-4-oxo-4H,6H,7H,8H,9H,10H-pyrimido[1,2-a]azepine-2-carboxamide

SMILES: Oc1c(nc2C(CCCCn2c1=O)N1CCOCC1)C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=CWVAOQNFCNBWNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22672 (Bicyclic pyrimidinone, 10c | N-[(4-fluorophenyl)me...) Show SMILES Oc1c(nc2C(CCCCn2c1=O)N1CCOCC1)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C21H25FN4O4/c22-15-6-4-14(5-7-15)13-23-20(28)17-18(27)21(29)26-8-2-1-3-16(19(26)24-17)25-9-11-30-12-10-25/h4-7,16,27H,1-3,8-13H2,(H,23,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	7.8	37
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 51: 861-74 (2008) Article DOI: 10.1021/jm701164t BindingDB Entry DOI: 10.7270/Q2765CNT
					More data for this Ligand-Target Pair