null

SMILES: Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=CFJVVGBJJLBPQF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230158 (US9340500, I-002) Show SMILES Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H32F3N3O2/c1-17-20(22(31)28-19-8-5-7-18(15-19)24(25,26)27)16-21(23(2,3)4)30(17)10-6-9-29-11-13-32-14-12-29/h5,7-8,15-16H,6,9-14H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	197	-9.51	n/a	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230158 (US9340500, I-002) Show SMILES Cc1c(cc(n1CCCN1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H32F3N3O2/c1-17-20(22(31)28-19-8-5-7-18(15-19)24(25,26)27)16-21(23(2,3)4)30(17)10-6-9-29-11-13-32-14-12-29/h5,7-8,15-16H,6,9-14H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair