null

SMILES: Cc1c(cc(-c2ccccc2)n1CCCN(CCO)CCO)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=AZSGJTXCLLMVJY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230172 (US9340500, I-016) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN(CCO)CCO)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H30F3N3O3/c1-19-23(25(35)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31(13-15-33)14-16-34/h2-5,7-10,17-18,33-34H,6,11-16H2,1H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	191	-9.53	n/a	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230172 (US9340500, I-016) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN(CCO)CCO)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H30F3N3O3/c1-19-23(25(35)30-22-10-5-9-21(17-22)26(27,28)29)18-24(20-7-3-2-4-8-20)32(19)12-6-11-31(13-15-33)14-16-34/h2-5,7-10,17-18,33-34H,6,11-16H2,1H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair