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SMILES: CC(C)c1cccc(NC(=O)c2cc(-c3ccccc3)n(CCCN3CCOCC3)c2C)c1

InChI Key: InChIKey=JAVSMUVFNKZROB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230185   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM230185
PNG
(US9340500, I-029)
Show SMILES CC(C)c1cccc(NC(=O)c2cc(-c3ccccc3)n(CCCN3CCOCC3)c2C)c1
Show InChI InChI=1S/C28H35N3O2/c1-21(2)24-11-7-12-25(19-24)29-28(32)26-20-27(23-9-5-4-6-10-23)31(22(26)3)14-8-13-30-15-17-33-18-16-30/h4-7,9-12,19-21H,8,13-18H2,1-3H3,(H,29,32)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
 519 -8.91n/an/an/an/an/an/a37



SHIONOGI & CO., LTD.

US Patent


Assay Description
Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...

US Patent US9340500 (2016)


BindingDB Entry DOI: 10.7270/Q2319TR3
More data for this
Ligand-Target Pair