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SMILES: CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CC1

InChI Key: InChIKey=ITRCJXLWFGXCQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230189   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM230189
PNG
(US9340500, I-033)
Show SMILES CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)CC1CC1
Show InChI InChI=1S/C27H30F3N3O/c1-19-24(26(34)31-23-11-6-10-22(16-23)27(28,29)30)17-25(21-8-4-3-5-9-21)33(19)15-7-14-32(2)18-20-12-13-20/h3-6,8-11,16-17,20H,7,12-15,18H2,1-2H3,(H,31,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 655 -8.77n/an/an/an/an/an/a37



SHIONOGI & CO., LTD.

US Patent


Assay Description
Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...

US Patent US9340500 (2016)


BindingDB Entry DOI: 10.7270/Q2319TR3
More data for this
Ligand-Target Pair