BindingDB logo
myBDB logout

null

SMILES: CN(C)CC(C)(C)CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=MGMYFEKOXVOISQ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230194   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM230194
PNG
(US9340500, I-038)
Show SMILES CN(C)CC(C)(C)CN(C)CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C30H39F3N4O/c1-22-26(28(38)34-25-15-10-14-24(18-25)30(31,32)33)19-27(23-12-8-7-9-13-23)37(22)17-11-16-36(6)21-29(2,3)20-35(4)5/h7-10,12-15,18-19H,11,16-17,20-21H2,1-6H3,(H,34,38)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 352 -9.15n/an/an/an/an/an/a37



SHIONOGI & CO., LTD.

US Patent


Assay Description
Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...

US Patent US9340500 (2016)


BindingDB Entry DOI: 10.7270/Q2319TR3
More data for this
Ligand-Target Pair