BDBM230241 US9340500, I-085

SMILES: FC(F)(F)c1cccc(NC(=O)c2cc(nn2CCCN2CCOCC2)-c2ccccc2)c1

InChI Key: InChIKey=JVGCUQBVYXBRCP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (TRPV4) (Homo sapiens (Human))	BDBM230241 (US9340500, I-085) Show SMILES FC(F)(F)c1cccc(NC(=O)c2cc(nn2CCCN2CCOCC2)-c2ccccc2)c1 Show InChI InChI=1S/C24H25F3N4O2/c25-24(26,27)19-8-4-9-20(16-19)28-23(32)22-17-21(18-6-2-1-3-7-18)29-31(22)11-5-10-30-12-14-33-15-13-30/h1-4,6-9,16-17H,5,10-15H2,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	590	-8.83	1.30E+3	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair