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SMILES: Cc1c(cc(n1CCS(=O)(=O)N1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=JTGQBGIARHGVTH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230254   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 4


(Homo sapiens (Human))		BDBM230254
PNG
(US9340500, I-098)
Show SMILES Cc1c(cc(n1CCS(=O)(=O)N1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C23H31F3N4O3S/c1-16-19(21(31)28-18-7-5-6-17(14-18)23(24,25)26)15-20(22(2,3)4)30(16)12-13-34(32,33)29-10-8-27-9-11-29/h5-7,14-15,27H,8-13H2,1-4H3,(H,28,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 590 -8.83 1.90E+3n/an/an/an/an/a37



SHIONOGI & CO., LTD.

US Patent


Assay Description
Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...

US Patent US9340500 (2016)


BindingDB Entry DOI: 10.7270/Q2319TR3
More data for this
Ligand-Target Pair