BDBM231571 US9345700, 6

SMILES: COc1cccc(c1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1

InChI Key: InChIKey=PRAAJLUHKMQDTB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231571 (US9345700, 6) Show SMILES COc1cccc(c1)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1 Show InChI InChI=1S/C26H19N3O3/c1-31-20-7-2-5-17(13-20)18-9-10-23-21(14-18)22(15-24(29-23)25-8-4-12-32-25)26(30)28-19-6-3-11-27-16-19/h2-16H,1H3,(H,28,30)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair