BDBM231581 US9345700, 16

SMILES: Cn1cnc2cc(ccc12)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1

InChI Key: InChIKey=ORNBXXOVMHCTMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231581 (US9345700, 16) Show SMILES Cn1cnc2cc(ccc12)-c1ccc2nc(cc(C(=O)Nc3cccnc3)c2c1)-c1ccco1 Show InChI InChI=1S/C27H19N5O2/c1-32-16-29-23-13-18(7-9-25(23)32)17-6-8-22-20(12-17)21(14-24(31-22)26-5-3-11-34-26)27(33)30-19-4-2-10-28-15-19/h2-16H,1H3,(H,30,33)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair