BDBM231585 US9345700, 20

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1c[nH]c2ccccc12)-c1ccco1

InChI Key: InChIKey=CFFLUBNAVUBZIH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231585 (US9345700, 20) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1c[nH]c2ccccc12)-c1ccco1 Show InChI InChI=1S/C27H18N4O2/c32-27(30-18-5-3-11-28-15-18)21-14-25(26-8-4-12-33-26)31-24-10-9-17(13-20(21)24)22-16-29-23-7-2-1-6-19(22)23/h1-16,29H,(H,30,32)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair