BDBM231586 US9345700, 21

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]c(=O)[nH]c2c1)-c1ccco1

InChI Key: InChIKey=QCQMWMKFTACUQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231586 (US9345700, 21) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2[nH]c(=O)[nH]c2c1)-c1ccco1 Show InChI InChI=1S/C26H17N5O3/c32-25(28-17-3-1-9-27-14-17)19-13-23(24-4-2-10-34-24)29-20-7-5-15(11-18(19)20)16-6-8-21-22(12-16)31-26(33)30-21/h1-14H,(H,28,32)(H2,30,31,33)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair