BDBM231587 US9345700, 22

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2ncccc2c1)-c1ccco1

InChI Key: InChIKey=HAAWAAMAKUVFGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231587 (US9345700, 22) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccc2ncccc2c1)-c1ccco1 Show InChI InChI=1S/C28H18N4O2/c33-28(31-21-5-2-11-29-17-21)23-16-26(27-6-3-13-34-27)32-25-10-8-19(15-22(23)25)18-7-9-24-20(14-18)4-1-12-30-24/h1-17H,(H,31,33)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair