BDBM231589 US9345700, 24

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(Nc3ccccn3)cc12)-c1ccco1

InChI Key: InChIKey=XQQOKGWFWLGQTB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231589 (US9345700, 24) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(Nc3ccccn3)cc12)-c1ccco1 Show InChI InChI=1S/C24H17N5O2/c30-24(28-17-5-3-10-25-15-17)19-14-21(22-6-4-12-31-22)29-20-9-8-16(13-18(19)20)27-23-7-1-2-11-26-23/h1-15H,(H,26,27)(H,28,30)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair