BDBM231592 US9345700, 27

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(NCCNc3ccccc3)cc12)-c1ccco1

InChI Key: InChIKey=VQDDKIRVBRKVTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231592 (US9345700, 27) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(NCCNc3ccccc3)cc12)-c1ccco1 Show InChI InChI=1S/C27H23N5O2/c33-27(31-21-8-4-12-28-18-21)23-17-25(26-9-5-15-34-26)32-24-11-10-20(16-22(23)24)30-14-13-29-19-6-2-1-3-7-19/h1-12,15-18,29-30H,13-14H2,(H,31,33)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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