BDBM231597 US9345700, 32

SMILES: CNC(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1

InChI Key: InChIKey=KHOCHWBXGQZTAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231597 (US9345700, 32) Show SMILES CNC(=O)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1 Show InChI InChI=1S/C22H15N3O2S/c1-23-22(26)16-11-18(20-3-2-8-27-20)25-17-6-4-13(9-15(16)17)14-5-7-21-19(10-14)24-12-28-21/h2-12H,1H3,(H,23,26)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair