BDBM231599 US9345700, 34

SMILES: Cc1nn(C)cc1-c1cc(C(=O)Nc2cccnc2)c2cc(ccc2n1)-c1ccccc1

InChI Key: InChIKey=VRRAOACMHRVKRW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231599 (US9345700, 34) Show SMILES Cc1nn(C)cc1-c1cc(C(=O)Nc2cccnc2)c2cc(ccc2n1)-c1ccccc1 Show InChI InChI=1S/C26H21N5O/c1-17-23(16-31(2)30-17)25-14-22(26(32)28-20-9-6-12-27-15-20)21-13-19(10-11-24(21)29-25)18-7-4-3-5-8-18/h3-16H,1-2H3,(H,28,32)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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