BDBM231603 US9345700, 38

SMILES: O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1cn[nH]c1

InChI Key: InChIKey=YYKAGQVUHIGRIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231603 (US9345700, 38) Show SMILES O=C(Nc1cccnc1)c1cc(nc2ccc(cc12)-c1ccccc1)-c1cn[nH]c1 Show InChI InChI=1S/C24H17N5O/c30-24(28-19-7-4-10-25-15-19)21-12-23(18-13-26-27-14-18)29-22-9-8-17(11-20(21)22)16-5-2-1-3-6-16/h1-15H,(H,26,27)(H,28,30)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair