BDBM231607 US9345700, 42

SMILES: O=C(NC1CCCCC1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1

InChI Key: InChIKey=BGFNRQGSBMGCQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231607 (US9345700, 42) Show SMILES O=C(NC1CCCCC1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1 Show InChI InChI=1S/C27H23N3O2S/c31-27(29-19-5-2-1-3-6-19)21-15-23(25-7-4-12-32-25)30-22-10-8-17(13-20(21)22)18-9-11-26-24(14-18)28-16-33-26/h4,7-16,19H,1-3,5-6H2,(H,29,31)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
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