BDBM231612 US9345700, 47

SMILES: O=C(Nc1ccccn1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1

InChI Key: InChIKey=JZMQVCUTWYHZKD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231612 (US9345700, 47) Show SMILES O=C(Nc1ccccn1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1 Show InChI InChI=1S/C26H16N4O2S/c31-26(30-25-5-1-2-10-27-25)19-14-21(23-4-3-11-32-23)29-20-8-6-16(12-18(19)20)17-7-9-24-22(13-17)28-15-33-24/h1-15H,(H,27,30,31)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair