BDBM231616 US9345700, 51

SMILES: O=C(Nc1nc2ccccc2[nH]1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1

InChI Key: InChIKey=OSTTUDUKTAMTQO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 231616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM231616 (US9345700, 51) Show SMILES O=C(Nc1nc2ccccc2[nH]1)c1cc(nc2ccc(cc12)-c1ccc2scnc2c1)-c1ccco1 Show InChI InChI=1S/C28H17N5O2S/c34-27(33-28-31-21-4-1-2-5-22(21)32-28)19-14-23(25-6-3-11-35-25)30-20-9-7-16(12-18(19)20)17-8-10-26-24(13-17)29-15-36-26/h1-15H,(H2,31,32,33,34)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eutropics Pharmaceuticals, Inc. US Patent					Assay Description A streptavidin-coated plate (Thermo Scientific, NUNC #436014) was washed three times with 300 μL of PBS-0.05% Tween solution. A biotinylated twent...				US Patent US9345700 (2016) BindingDB Entry DOI: 10.7270/Q2J38RD4
					More data for this Ligand-Target Pair