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Enter Data
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SMILES: CCCCNC(=O)\C=C\c1cc(OC)c(OC)c(OC)c1
InChI Key: InChIKey=LUEZYPDVMFFBEP-BQYQJAHWSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 27 |
Ewha Womans University | Assay Description For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM232200 ((E)-N-Butyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ewha Womans University | Assay Description Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]... | J Enzyme Inhib Med Chem 25: 38-43 (2010) Article DOI: 10.3109/14756360902932784 BindingDB Entry DOI: 10.7270/Q2F76BDV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
