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SMILES: CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CC(C)C)C(C)C)C(=O)NCCc1ccccc1

InChI Key: InChIKey=FLAUZUZEPIDNDF-QMFIVWORSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232266   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Homo sapiens (Human))		BDBM232266
PNG
(US9345742, 24)
Show SMILES CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CC(C)C)C(C)C)C(=O)NCCc1ccccc1 |r|
Show InChI InChI=1S/C41H64N6O5/c1-9-29(8)38(40(51)43-21-20-30-16-12-10-13-17-30)46-36(49)25-32(42)33(24-31-18-14-11-15-19-31)45-41(52)37(28(6)7)47-39(50)34(22-26(2)3)44-35(48)23-27(4)5/h10-19,26-29,32-34,37-38H,9,20-25,42H2,1-8H3,(H,43,51)(H,44,48)(H,45,52)(H,46,49)(H,47,50)/t29-,32-,33-,34-,37-,38-/m0/s1
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PC cid
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US Patent
n/an/a 240n/an/an/an/a5.525



MERCK PATENT GMBH

US Patent


Assay Description
In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...

US Patent US9345742 (2016)


BindingDB Entry DOI: 10.7270/Q25Q4TZD
More data for this
Ligand-Target Pair