BDBM23240 1,2,5-oxadiazole, OXD8::4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}-1,2,5-oxadiazole-3-carboxylic acid

SMILES: OC(=O)c1nonc1OC\C=C\c1ccccc1

InChI Key: InChIKey=FPMGMIKUFWQUDM-QPJJXVBHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lactate dehydrogenase B (LDHB) (Homo sapiens (Human))	BDBM23240 (1,2,5-oxadiazole, OXD8 | 4-{[(2E)-3-phenylprop-2-e...) Show SMILES OC(=O)c1nonc1OC\C=C\c1ccccc1 Show InChI InChI=1S/C12H10N2O4/c15-12(16)10-11(14-18-13-10)17-8-4-7-9-5-2-1-3-6-9/h1-7H,8H2,(H,15,16)/b7-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol					Assay Description An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...				J Biol Chem 279: 31429-39 (2004) Article DOI: 10.1074/jbc.M402433200 BindingDB Entry DOI: 10.7270/Q2CR5RN4
					More data for this Ligand-Target Pair
Lactate Dehydrogenase (Plasmodium falciparum)	BDBM23240 (1,2,5-oxadiazole, OXD8 | 4-{[(2E)-3-phenylprop-2-e...) Show SMILES OC(=O)c1nonc1OC\C=C\c1ccccc1 Show InChI InChI=1S/C12H10N2O4/c15-12(16)10-11(14-18-13-10)17-8-4-7-9-5-2-1-3-6-9/h1-7H,8H2,(H,15,16)/b7-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	7.5	25
University of Bristol					Assay Description An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...				J Biol Chem 279: 31429-39 (2004) Article DOI: 10.1074/jbc.M402433200 BindingDB Entry DOI: 10.7270/Q2CR5RN4
					More data for this Ligand-Target Pair				3D Structure (docked)