BDBM232942 US9351973, 12::US9844553, 12
SMILES: CN1c2c(C)c(nn2CCC1=O)-c1cncc(F)c1
InChI Key: InChIKey=ZNUSXAVKKIGLRC-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human)) | BDBM232942 (US9351973, 12 | US9844553, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19.1 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ... | US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1 (Homo sapiens (Human)) | BDBM232942 (US9351973, 12 | US9844553, 12) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme... | US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2 (Homo sapiens (Human)) | BDBM232942 (US9351973, 12 | US9844553, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme... | US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM232942 (US9351973, 12 | US9844553, 12) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ... | US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC | |||||||||||
More data for this Ligand-Target Pair |