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SMILES: Cc1ccc(COc2ccc(\C=C\C(=O)NO)cc2)cc1

InChI Key: InChIKey=QTJXDPTVIBMFFE-DHZHZOJOSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232984   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2


(Homo sapiens (Human))		BDBM232984
PNG
((E)-3-(4-(4-methylbenzyloxy)phenyl)-N-hydroxyacryl...)
Show SMILES Cc1ccc(COc2ccc(\C=C\C(=O)NO)cc2)cc1
Show InChI InChI=1S/C17H17NO3/c1-13-2-4-15(5-3-13)12-21-16-9-6-14(7-10-16)8-11-17(19)18-20/h2-11,20H,12H2,1H3,(H,18,19)/b11-8+
PDB

UniProtKB/SwissProt

antibodypedia
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GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.35E+4n/an/an/an/an/an/a



Shan Dong University



Assay Description
In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...

J Enzyme Inhib Med Chem 25: 132-8 (2010)


Article DOI: 10.3109/14756360903049034
BindingDB Entry DOI: 10.7270/Q2MS3RNW
More data for this
Ligand-Target Pair