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SMILES: ONC(=O)\C=C\c1ccc(OCc2ccc(Cl)cc2)cc1

InChI Key: InChIKey=UKFIJXAAAWXQKV-BJMVGYQFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232988   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2


(Homo sapiens (Human))		BDBM232988
PNG
((E)-3-(4-(4-chlorobenzyloxy)phenyl)-N-hydroxyacryl...)
Show SMILES ONC(=O)\C=C\c1ccc(OCc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C16H14ClNO3/c17-14-6-1-13(2-7-14)11-21-15-8-3-12(4-9-15)5-10-16(19)18-20/h1-10,20H,11H2,(H,18,19)/b10-5+
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Shan Dong University



Assay Description
In vitro bioactivity evaluation of compounds 4a-n was performed by HDAC activity assays using a HDAC colorimetric activity assay kit (AK501; Biomol R...

J Enzyme Inhib Med Chem 25: 132-8 (2010)


Article DOI: 10.3109/14756360903049034
BindingDB Entry DOI: 10.7270/Q2MS3RNW
More data for this
Ligand-Target Pair