BDBM233084 mtFabH inhibitor, 31
SMILES: CC1=C(O)C(C)(Cc2ccc(cc2)-c2cc(F)cc(F)c2)SC1=O
InChI Key: InChIKey=BYTCNDXHSJPLDO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β-Ketoacyl-acyl carrier protein (ACP) synthase III (FabH) (Mycobacterium tuberculosis) | BDBM233084 (mtFabH inhibitor, 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The biological activities of the compounds were evaluated in the same laboratory. Biological activities measured as IC50 were converted to pIC50 (... | J Enzyme Inhib Med Chem 25: 240-9 (2010) Article DOI: 10.3109/14756360903049059 BindingDB Entry DOI: 10.7270/Q22R3QJT | |||||||||||
More data for this Ligand-Target Pair |