BDBM233271 US9346786, 75

SMILES: CCN([C@@H]1CN(C[C@H]1c1ccc(Cl)c(F)c1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)cn1)C(=O)Oc1ccc(F)cc1

InChI Key: InChIKey=TXSPZUXEGDDBOU-RBJSKKJNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM233271 (US9346786, 75) Show SMILES CCN([C@@H]1CN(C[C@H]1c1ccc(Cl)c(F)c1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)cn1)C(=O)Oc1ccc(F)cc1 |r| Show InChI InChI=1S/C31H30ClF3N4O4/c1-2-39(31(42)43-23-7-4-21(33)5-8-23)28-18-38(17-24(28)20-3-9-25(32)26(35)15-20)29(40)19-11-13-37(14-12-19)30(41)27-10-6-22(34)16-36-27/h3-10,15-16,19,24,28H,2,11-14,17-18H2,1H3/t24-,28+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	-10.8	n/a	n/a	n/a	n/a	n/a	7.4	4
Hoffmann-La Roche Inc. US Patent					Assay Description hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...				US Patent US9346786 (2016) BindingDB Entry DOI: 10.7270/Q20V8BPC
					More data for this Ligand-Target Pair