BDBM235235 US9365558, 58::US9822074, 58

SMILES: FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)c1ccc2CCCCc2c1)C(F)(F)F

InChI Key: InChIKey=ZBIGUWQYMXNXCZ-MHZLTWQESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235235 (US9365558, 58 | US9822074, 58) Show SMILES FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)c1ccc2CCCCc2c1)C(F)(F)F |r,t:17| Show InChI InChI=1S/C29H32F6N4O4S/c30-28(31,32)12-4-1-5-13-39-17-21(16-36-39)27(29(33,34)35)15-23(20-9-8-18-6-2-3-7-19(18)14-20)24(25(40)37-27)26(41)38-44(42,43)22-10-11-22/h8-9,14,16-17,22H,1-7,10-13,15H2,(H,37,40)(H,38,41)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235235 (US9365558, 58 | US9822074, 58) Show SMILES FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)c1ccc2CCCCc2c1)C(F)(F)F |r,t:17| Show InChI InChI=1S/C29H32F6N4O4S/c30-28(31,32)12-4-1-5-13-39-17-21(16-36-39)27(29(33,34)35)15-23(20-9-8-18-6-2-3-7-19(18)14-20)24(25(40)37-27)26(41)38-44(42,43)22-10-11-22/h8-9,14,16-17,22H,1-7,10-13,15H2,(H,37,40)(H,38,41)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair