BDBM235236 US9365558, 59::US9822074, 59

SMILES: FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(c2ccc(s2)C2CC2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F

InChI Key: InChIKey=LVRCPAITBBEACY-DEOSSOPVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235236 (US9365558, 59 | US9822074, 59) Show SMILES FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(c2ccc(s2)C2CC2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:27| Show InChI InChI=1S/C26H28F6N4O4S2/c27-25(28,29)10-2-1-3-11-36-14-16(13-33-36)24(26(30,31)32)12-18(20-9-8-19(41-20)15-4-5-15)21(22(37)34-24)23(38)35-42(39,40)17-6-7-17/h8-9,13-15,17H,1-7,10-12H2,(H,34,37)(H,35,38)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235236 (US9365558, 59 | US9822074, 59) Show SMILES FC(F)(F)CCCCCn1cc(cn1)[C@@]1(CC(c2ccc(s2)C2CC2)=C(C(=O)NS(=O)(=O)C2CC2)C(=O)N1)C(F)(F)F |r,t:27| Show InChI InChI=1S/C26H28F6N4O4S2/c27-25(28,29)10-2-1-3-11-36-14-16(13-33-36)24(26(30,31)32)12-18(20-9-8-19(41-20)15-4-5-15)21(22(37)34-24)23(38)35-42(39,40)17-6-7-17/h8-9,13-15,17H,1-7,10-12H2,(H,34,37)(H,35,38)/t24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair