null
SMILES: CN1CCN(CC1)c1cnc2c(NCCCn3cncn3)nc(nc2n1)-c1ccccc1
InChI Key: InChIKey=RNHZXCWUEBJJPH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 9 (Homo sapiens (Human)) | BDBM235722 (US10117875, Example 64 | US9359361, 64) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
JANUS BIOTHERAPEUTICS, INC. US Patent | Assay Description HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu... | US Patent US10117875 (2018) BindingDB Entry DOI: 10.7270/Q2MK6FXT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 9 (Homo sapiens (Human)) | BDBM235722 (US10117875, Example 64 | US9359361, 64) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
JANUS BIOTHERAPEUTICS, INC. US Patent | Assay Description Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre... | US Patent US9359361 (2016) BindingDB Entry DOI: 10.7270/Q2GH9GT3 | |||||||||||
More data for this Ligand-Target Pair |