BDBM235774 US9359372, DC037024

SMILES: COc1cc2CC3N(CCc4cc(O)c(O)cc34)Cc2cc1OC

InChI Key: InChIKey=BTUIZHMEGKWEMO-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM235774 (US9359372, DC037024) Show SMILES COc1cc2CC3N(CCc4cc(O)c(O)cc34)Cc2cc1OC Show InChI InChI=1S/C19H21NO4/c1-23-18-7-12-5-15-14-9-17(22)16(21)6-11(14)3-4-20(15)10-13(12)8-19(18)24-2/h6-9,15,21-22H,3-5,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	741	-8.50	1.50E+3	n/a	n/a	n/a	n/a	n/a	30
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES US Patent					Assay Description Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...				US Patent US9359372 (2016) BindingDB Entry DOI: 10.7270/Q2736PSP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM235774 (US9359372, DC037024) Show SMILES COc1cc2CC3N(CCc4cc(O)c(O)cc34)Cc2cc1OC Show InChI InChI=1S/C19H21NO4/c1-23-18-7-12-5-15-14-9-17(22)16(21)6-11(14)3-4-20(15)10-13(12)8-19(18)24-2/h6-9,15,21-22H,3-5,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	591	n/a	n/a	n/a	37
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES US Patent					Assay Description Each medicament was dissolved in serum-free F12 culture medium containing 100 μM of IBMX. CHO cells which can stably express D2 receptor were pre-...				US Patent US9359372 (2016) BindingDB Entry DOI: 10.7270/Q2736PSP
					More data for this Ligand-Target Pair