BDBM236525 2-Methoxy-10-[(2-N,N-dimethylamino-2-ethyl)ethyl]benzo[d]isothiazolo[3,2-a]indol-S,S-dioxide (16)

SMILES: CCC(CC1=C2C(c3ccc(OC)cc13)S(=O)(=O)c1ccccc21)N(C)C

InChI Key: InChIKey=IYESPJOMEMMYMO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236525 (2-Methoxy-10-[(2-N,N-dimethylamino-2-ethyl)ethyl]b...) Show SMILES CCC(CC1=C2C(c3ccc(OC)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:4| Show InChI InChI=1S/C22H25NO3S/c1-5-14(23(2)3)12-19-18-13-15(26-4)10-11-16(18)22-21(19)17-8-6-7-9-20(17)27(22,24)25/h6-11,13-14,22H,5,12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28.3	-10.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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