BDBM236530 2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]isoindolo[2,1-a] indole (21)

SMILES: CC(C)Oc1ccc2C3Cc4ccccc4C3=C(CC(C)N(C)C)c2c1

InChI Key: InChIKey=WLWFEYZLDFHAEB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236530 (2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)eth...) Show SMILES CC(C)Oc1ccc2C3Cc4ccccc4C3=C(CC(C)N(C)C)c2c1 |t:18| Show InChI InChI=1S/C24H29NO/c1-15(2)26-18-10-11-20-21(14-18)22(12-16(3)25(4)5)24-19-9-7-6-8-17(19)13-23(20)24/h6-11,14-16,23H,12-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	73.2	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
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