BDBM236536 2,4-Difluoro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,1-a]indole (27)

SMILES: CN(C)CCC1=C2C(Cc3ccccc23)c2c1cc(F)cc2F

InChI Key: InChIKey=JKIOQCNXXURSHF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236536 (2,4-Difluoro-10-(2-N,N-dimethylaminoethyl)isoindol...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2c1cc(F)cc2F |t:5| Show InChI InChI=1S/C20H19F2N/c1-23(2)8-7-15-16-10-13(21)11-18(22)20(16)17-9-12-5-3-4-6-14(12)19(15)17/h3-6,10-11,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	153	-9.66	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair