BDBM236541 10-[(2-N,N-Dimethylamino-2-methyl)ethyl]isoindolo[2,1-a]indol-5-one (32)

SMILES: CC(CC1=C2C(C(=O)c3ccccc23)c2ccccc12)N(C)C

InChI Key: InChIKey=YHNKAIWERURGDX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236541 (10-[(2-N,N-Dimethylamino-2-methyl)ethyl]isoindolo[...) Show SMILES CC(CC1=C2C(C(=O)c3ccccc23)c2ccccc12)N(C)C |t:3| Show InChI InChI=1S/C21H21NO/c1-13(22(2)3)12-18-14-8-4-5-9-15(14)20-19(18)16-10-6-7-11-17(16)21(20)23/h4-11,13,20H,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	296	-9.26	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair