BDBM23666 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(butylamino)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol::Dipyridamole Analogue, 48

SMILES: CCCCNc1nc(nc2c(NCCCC)nc(nc12)N(CCO)CCO)N(CCO)CCO

InChI Key: InChIKey=JULBPHOIANSTAP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human))	BDBM23666 (2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(butylamin...) Show SMILES CCCCNc1nc(nc2c(NCCCC)nc(nc12)N(CCO)CCO)N(CCO)CCO Show InChI InChI=1S/C22H40N8O4/c1-3-5-7-23-19-17-18(26-21(27-19)29(9-13-31)10-14-32)20(24-8-6-4-2)28-22(25-17)30(11-15-33)12-16-34/h31-34H,3-16H2,1-2H3,(H,23,26,27)(H,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	136	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...				J Med Chem 50: 3906-20 (2007) Article DOI: 10.1021/jm070311l BindingDB Entry DOI: 10.7270/Q2XK8CVN
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