BDBM23667 2-{[4,8-bis(butylamino)-6-[(2-hydroxyethyl)amino]pyrimido[5,4-d][1,3]diazin-2-yl]amino}ethan-1-ol::Dipyridamole Analogue, 49

SMILES: CCCCNc1nc(NCCO)nc2c(NCCCC)nc(NCCO)nc12

InChI Key: InChIKey=YSZSAMOEPLHXNZ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human))	BDBM23667 (2-{[4,8-bis(butylamino)-6-[(2-hydroxyethyl)amino]p...) Show SMILES CCCCNc1nc(NCCO)nc2c(NCCCC)nc(NCCO)nc12 Show InChI InChI=1S/C18H32N8O2/c1-3-5-7-19-15-13-14(24-17(25-15)21-9-11-27)16(20-8-6-4-2)26-18(23-13)22-10-12-28/h27-28H,3-12H2,1-2H3,(H2,19,21,24,25)(H2,20,22,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	489	n/a	8.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...				J Med Chem 50: 3906-20 (2007) Article DOI: 10.1021/jm070311l BindingDB Entry DOI: 10.7270/Q2XK8CVN
					More data for this Ligand-Target Pair