BDBM236928 US9388189, 20

SMILES: Nc1ncnc(N[C@@H](CCOc2ccccc2)c2nn3cccc3c(=O)n2-c2ccccc2)c1C#N

InChI Key: InChIKey=XTYIFCPPYJBJJL-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM236928 (US9388189, 20) Show SMILES Nc1ncnc(N[C@@H](CCOc2ccccc2)c2nn3cccc3c(=O)n2-c2ccccc2)c1C#N Show InChI InChI=1S/C26H22N8O2/c27-16-20-23(28)29-17-30-24(20)31-21(13-15-36-19-10-5-2-6-11-19)25-32-33-14-7-12-22(33)26(35)34(25)18-8-3-1-4-9-18/h1-12,14,17,21H,13,15H2,(H3,28,29,30,31)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description PI-3 Kinase HTRF kit (ref. #33-037) and the different PI3K recombinant isoforms (ref. #14-602, ref. #14-603, ref. #14-604, ref. #15-558 for Alpha, Be...				US Patent US9388189 (2016) BindingDB Entry DOI: 10.7270/Q2K64H0P
					More data for this Ligand-Target Pair