BDBM23693 2-[(6-{bis[2-(acetyloxy)ethyl]amino}-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl)[2-(acetyloxy)ethyl]amino]ethyl acetate::Dipyridamole Analogue, 75

SMILES: CC(=O)OCCN(CCOC(C)=O)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOC(C)=O)CCOC(C)=O

InChI Key: InChIKey=NAQKJRWKMHLFAE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human))	BDBM23693 (2-[(6-{bis[2-(acetyloxy)ethyl]amino}-4,8-bis(piper...) Show SMILES CC(=O)OCCN(CCOC(C)=O)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOC(C)=O)CCOC(C)=O Show InChI InChI=1S/C32H48N8O8/c1-23(41)45-19-15-39(16-20-46-24(2)42)31-33-27-28(29(35-31)37-11-7-5-8-12-37)34-32(36-30(27)38-13-9-6-10-14-38)40(17-21-47-25(3)43)18-22-48-26(4)44/h5-22H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17.1	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...				J Med Chem 50: 3906-20 (2007) Article DOI: 10.1021/jm070311l BindingDB Entry DOI: 10.7270/Q2XK8CVN
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