BDBM23694 2-N,2-N,6-N,6-N-tetrakis(2-methoxyethyl)-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazine-2,6-diamine::Dipyridamole Analogue, 76

SMILES: COCCN(CCOC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOC)CCOC

InChI Key: InChIKey=GDAALJDXRYUSDN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human))	BDBM23694 (2-N,2-N,6-N,6-N-tetrakis(2-methoxyethyl)-4,8-bis(p...) Show SMILES COCCN(CCOC)c1nc(N2CCCCC2)c2nc(nc(N3CCCCC3)c2n1)N(CCOC)CCOC Show InChI InChI=1S/C28H48N8O4/c1-37-19-15-35(16-20-38-2)27-29-23-24(25(31-27)33-11-7-5-8-12-33)30-28(36(17-21-39-3)18-22-40-4)32-26(23)34-13-9-6-10-14-34/h5-22H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	91.6	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tennessee Health Science Center					Assay Description The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...				J Med Chem 50: 3906-20 (2007) Article DOI: 10.1021/jm070311l BindingDB Entry DOI: 10.7270/Q2XK8CVN
					More data for this Ligand-Target Pair