null

SMILES: C[C@H](Nc1ncnc2[nH]cc(-c3ccn(CCN4CCOCC4)n3)c12)c1nn2ccc(C)c2c(=O)n1-c1ccccc1

InChI Key: InChIKey=LIMWFKHHOCVUJT-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM236969 (US9388189, 144) Show SMILES C[C@H](Nc1ncnc2[nH]cc(-c3ccn(CCN4CCOCC4)n3)c12)c1nn2ccc(C)c2c(=O)n1-c1ccccc1 Show InChI InChI=1S/C30H32N10O2/c1-20-8-11-39-26(20)30(41)40(22-6-4-3-5-7-22)29(36-39)21(2)34-28-25-23(18-31-27(25)32-19-33-28)24-9-10-38(35-24)13-12-37-14-16-42-17-15-37/h3-11,18-19,21H,12-17H2,1-2H3,(H2,31,32,33,34)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description PI-3 Kinase HTRF kit (ref. #33-037) and the different PI3K recombinant isoforms (ref. #14-602, ref. #14-603, ref. #14-604, ref. #15-558 for Alpha, Be...				US Patent US9388189 (2016) BindingDB Entry DOI: 10.7270/Q2K64H0P
					More data for this Ligand-Target Pair